HK EB3-EGFP Cells

Hela Kyoto EB3-EGFP is a derivative of the HeLa Kyoto cell line, specifically engineered to express the End-Binding Protein 3 (EB3) tagged with Enhanced Green Fluorescent Protein (EGFP). This cell line is commonly utilized in research focused on understanding microtubule dynamics due to the fluorescent tagging of EB3, a protein that associates with the plus ends of microtubules. The expression of EGFP provides a fluorescent marker that allows for real-time visualization of microtubule behavior in live cells under a fluorescence microscope.

This cell line is particularly valuable in cell biology and cancer research, where understanding the mechanics of cell division and intracellular transport is crucial. The stable expression of EB3-EGFP does not interfere with the normal functions of the microtubules, making these cells a reliable tool for detailed studies of cellular processes that depend on microtubule dynamics.